Arthur Nathaniel Billings blood disorder ITP health advices 2022? What is ITP? Immune thrombocytopenia (formerly known as idiopathic thrombocytopenic purpura) is a medical term for an autoimmune disorder (immune) causing a shortage of platelets (thrombocytopenia) and bruising (purpura). What is the cause of ITP? ITP is an autoimmune disease in which the immune system mistakes the platelets as being foreign and destroys them. It can follow a virus, vaccination or certain medications, but for most people the cause is unknown.
Arthur Nathaniel Billings on ITP blood disorder treatments : What is the incidence of ITP? In the USA about 3,000 to 4,000 of the population have ITP at any one time, and it is not more prevalent in any particular racial or ethnic group. What are the symptoms of ITP? Some people with ITP, especially those with a count over 50, may have no symptoms at all, and their ITP only noticed during a routine blood test. Even people with very low counts, can sometimes have few symptoms.
What causes ITP? ITP is an autoimmune disease. In some cases, this is due to a self-reacting antibody binding to the surface of the platelets, causing both to be removed by cells in the spleen and elsewhere. However, other immune abnormalities have been found in some patients with ITP that affect lymphocytes (a type of white cell) or megakaryocytes (the precursor cells of platelets). These differences may help explain why patients vary in their response to treatment. Why some people develop this “autoimmune” process and others do not is not fully understood. In some individuals, a viral infection may act as an environmental trigger to the process and your doctors may test for triggers such as infection when you are first assessed.
Steroids. Steroids help prevent bleeding by reducing the rate of platelet destruction. Steroids, if effective, will result in an increase in platelet counts seen within 2 to 3 weeks. Side effects may include irritability, stomach irritation, weight gain, high blood pressure, and acne. Intravenous gamma globulin (IVGG). Intravenous gamma globulin (IVGG) is a protein that contains many antibodies and also slows the destruction of platelets. IVGG works faster than steroids (within 24 to 48 hours). Find more info on Arthur Billings.
Thrombocytopenia means a decreased number of platelets in the blood. Purpura refers to the purple discoloring of the skin, as with a bruise. ITP is a fairly common blood disorder that both children and adults can develop. There are two forms of ITP: Acute thrombocytopenic purpura. This usually affects young children, ages 2 to 6 years old. The symptoms may follow a viral illness, such as chickenpox. Acute ITP usually starts suddenly and the symptoms usually disappear in less than 6 months, often within a few weeks. Treatment is often not needed. The disorder usually does not recur. Acute ITP is the most common form of the disorder.